I have a question... so perhap's it's stupid....

I am the only user of this fantastic software on my computer, no lan, no another users, and I often have some problems when I want to save my list file !!!
- "the file is protect in writing"
Sometimes it's ok but not ever...
And I can't save the file in another directory, with a different name...
Can you help me please ?

Thanks a lot !
RV